Myosin X dimerization and its impact on cellular functions

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Myosin X dimerization and its impact on cellular functions.

A ll members of the myosin superfamily of actin-based molecular motors are thought to use the energy from ATP hydrolysis to generate force and motion. Some myosins are capable of forming parallel coiled-coil dimers by virtue of a coiled-coil domain that is C-terminal to the motor catalytic region (head) (1). This form of dimerization is thought to be essential for the hand-over-hand processive ...

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ژورنال

عنوان ژورنال: Proceedings of the National Academy of Sciences

سال: 2012

ISSN: 0027-8424,1091-6490

DOI: 10.1073/pnas.1216035109